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Doctors writing in a prominent medical journal, The New England Journal of Medicine, recommended that physicians stop prescribing Pfizer's Bextra® painkiller, just as a large study found the drug maker's sister drug Celebrex®, doubled risk of heart attacks.
A letter by three top doctors published in the medical journal said that in light of Vioxx® and negative signs on Bextra®, Bextra® should be avoided.
"We believe the doubts raised about the safety of Bextra®, constitute a potential imminent hazard to public health" and thus they say should be prescribed only in "extraordinary circumstances," editorial writers at The New England Journal of Medicine wrote in an issue released last Friday.
The authors of the medical journal are doctors at the Vanderbilt University School of Medicine. They state that they made the recommendation in light of the long lag time between when evidence emerged on Vioxx® and its withdrawal, coupled with two negative studies suggesting Bextra® boosts heart problems in bypass patients by a factor of three.
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